The Alzheimer's Association, Maine Chapter was incorporated in 1987. The founder was Marilyn Paige, whose husband was diagnosed with Alzheimer’s disease in 1981. Like others whose loved ones become ill with Alzheimer’s, Marilyn felt she needed help in assuming her new role as caregiver. Unable to find a support network, she started a support group of her own in February 1982, which met at the United Methodist Church in West Scarborough. With a little publicity in the local newspapers, the number of people in her support group soon reached twenty-five.

By 1984, there were 14 support groups in Maine and an organization was beginning to develop. In the same year, Paige founded the Maine Alzheimer’s Disease Association. In 1987, the organization became affiliated with the National Alzheimer’s Association and was incorporated as the Alzheimer's Association, Maine Chapter . In 1992, the Chapter opened its first office in Scarborough, moving its base of operations from Marilyn Paige’s home, and in 1993, a part-time Executive Director, the Chapter’s first, was hired. The office relocated to Portland in 1995 and a full-time Executive Director was hired in January, 1996.

The Alzheimer's Association, Maine Chapter is located in Portland, Maine and is a chapter of the National Alzheimer's Association. A statewide Board of Directors, consisting of caregivers, family members, health care professionals, civic and business leaders governs the chapter and provides strategic leadership and direction for the organization. The Alzheimer's Association, Maine Chapter serves the entire state of Maine and includes 13 staff members responsible for education, public awareness, advocacy, patient and family services, development and management.